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KSQ-4279
SKU
HY-145471-10 mg
Category Reference compound
Tags Apoptosis;Cell Cycle/DNA Damage, Apoptosis;Deubiquitinase, Cancer
$800 – $1,280
Products Details
Product Description
– KSQ-4279 (USP1-IN-1) is a potent, first-in-class, and highly selective USP1 inhibitor. KSQ-4279 shows anticancer effects[1].
Web ID
– HY-145471
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C27H25F3N8O
References
– [1]Natalie Y L Ngoi, et al. Targeting the DNA damage response beyond poly(ADP-ribose) polymerase inhibitors: novel agents and rational combinations. Curr Opin Oncol. 2022 Sep 1;34(5):559-569.
CAS Number
– 2446480-97-1
Molecular Weight
– 534.54
Compound Purity
– 99.94
SMILES
– FC(F)(C1=CN(C(C)C)C(C2=CC=C(CN3N=CC4=C3N=C(C5=C(C6CC6)N=CN=C5OC)N=C4)C=C2)=N1)F
Clinical Information
– Phase 1
Research Area
– Cancer
Solubility
– DMSO : 80 mg/mL (ultrasonic)
Target
– Apoptosis;Deubiquitinase
Pathway
– Apoptosis;Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.