KSQ-4279

$800$1,280

Products Details

Product Description

– KSQ-4279 (USP1-IN-1) is a potent, first-in-class, and highly selective USP1 inhibitor. KSQ-4279 shows anticancer effects[1].

Web ID

– HY-145471

Storage Temperature

– -20°C, 3 years (Powder)

Shipping

– Blue Ice

Applications

– Cancer-programmed cell death

Molecular Formula

– C27H25F3N8O

References

– [1]Natalie Y L Ngoi, et al. Targeting the DNA damage response beyond poly(ADP-ribose) polymerase inhibitors: novel agents and rational combinations. Curr Opin Oncol. 2022 Sep 1;34(5):559-569.

CAS Number

– 2446480-97-1

Molecular Weight

– 534.54

Compound Purity

– 99.94

SMILES

– FC(F)(C1=CN(C(C)C)C(C2=CC=C(CN3N=CC4=C3N=C(C5=C(C6CC6)N=CN=C5OC)N=C4)C=C2)=N1)F

Clinical Information

– Phase 1

Research Area

– Cancer

Solubility

– DMSO : 80 mg/mL (ultrasonic)

Target

– Apoptosis;Deubiquitinase

Pathway

– Apoptosis;Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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