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Products Details
Product Description
– KSK68 is a high-affinity dual sigma-1 and histamine H3 receptor antagonist, with Kis of 7.7, 3.6, 22.4 nM for H3 receptor, sigma-1, sigma-2 receptor respectively. KSK68 has negligible affinity at the other histamine receptor subtypes. KSK68 can be used for research of nociceptive and neuropathic pain[1].
Web ID
– HY-155614
Shipping
– Room temperature
Molecular Formula
– C23H28N2O2
References
– [1]Szczepańska K, et al. Dual Piperidine-Based Histamine H3 and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain. J Med Chem. 2023 Jul 27;66(14):9658-9683.
CAS Number
– 2566715-91-9
Molecular Weight
– 364.48
SMILES
– O=C(C1CC1)C2=CC=C(OCCCN3CCC(C4=CC=NC=C4)CC3)C=C2
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Histamine Receptor;Sigma Receptor
Pathway
– GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
