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KRASG12D-IN-1
$400 – $990
Products Details
Product Description
– KRASG12D-IN-1 (compound 22) is a KRASG12D Inhibitor. KRASG12D-IN-1 has dose-dependent anti-tumor efficacy in the AsPC-1 xenograft mouse models with a tumor growth inhibition[1].
Web ID
– HY-157029S
Shipping
– Room temperature
Molecular Formula
– C34H28D2F4N6O2
References
– [1]Xiao X, et al. Design, Synthesis, and Pharmacological Evaluation of Multisubstituted Pyrido[4,3-d]pyrimidine Analogues Bearing Deuterated Methylene Linkers as Potent KRASG12D Inhibitors. J Med Chem. 2023 Nov 3.
Molecular Weight
– 632.65
SMILES
– FC1=C(C2=CN=C1C3=C4C(C#C)=C(C=CC4=CC(O)=C3)F)N=C(N=C2N5C[C@H](CC6)N[C@H]6C5)OC([2H])(C78CCCN7C/C(C8)=C(F)F)[2H]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ras
Pathway
– GPCR/G Protein
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
