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KRASG12C IN-2
Products Details
Product Description
– KRASG12C IN-2 (compound 17) is an orally active KRASG12C inhibitor. KRASG12C IN-2 inhibits tumor growth in mice[1].
Web ID
– HY-153262
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C32H35F6N7O3
References
– [1]Zhang Yang, et al. Pyrimidoheterocyclic compounds and application thereof. WO2021180181A1.
CAS Number
– 2706637-12-7
Molecular Weight
– 679.66
SMILES
– FC(F)(F)C(C(C)=CC(N)=C1F)=C1[C@H]2CC3=NC(OC[C@@]45N(CCC5)C[C@@H](C4)F)=NC(N6C[C@@H](N(CC6)C(C(F)=C)=O)CC#N)=C3CO2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ras
Pathway
– GPCR/G Protein
Product type
– Reference compound
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