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KRAS G12D inhibitor 8
Products Details
Product Description
– KRAS G12D inhibitor 8 is a potent inhibitor of KRAS G12D. The Ras family of proteins is an important intracellular signaling molecule that plays an important role in growth and development. KRAS G12D inhibitor 8 has the potential for the research of KRAS G12D-mediated cancer (extracted from patent WO2021107160A1, compound 2)[1].
Web ID
– HY-143599
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C32H38BrFN6O2
References
– [1]Yuichi Kawai, et al. A compound having inhibitory activity against kras g12d mutation. Patent WO2021107160A1.
CAS Number
– 2648221-05-8
Molecular Weight
– 637.59
SMILES
– OC1=CC(C=CC=C2Br)=C2C(N3CC4=NC(OCC5(CC5)CN6C[C@@H](CC6)F)=NC(N7CC8NC(CC8)C7)=C4CC3)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ras
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.