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Products Details
Product Description
– KRAS G12D inhibitor 16 is a KRAS G12D inhibitor. KRAS G12D inhibitor 16 has inhibitory activity against KRAS G12D and KRAS G12D mutation with IC50 value of 0.7 nM and 0.35 μM, respectively. KRAS G12D inhibitor 16 can be used for the research of many malignant tumor, such as pancreatic ductal adenocarcinomas (PDAC), colon and rectal carcinomas (CRC), non-small cell lung carcinomas (NSCLC)[1].
Web ID
– HY-148260
Shipping
– Room temperature
Molecular Formula
– C32H39IN6O3
References
– [1]Yuichi Kawai, et al. A compound having inhibitory activity against kras g12d mutation. Patent. WO2021107160A1.
CAS Number
– 2648221-12-7
Molecular Weight
– 682.59
SMILES
– IC1=CC=CC2=C1C(N3CC(N=C(OCC4(CC4)CN5CCOCC5)N=C6N7C[C@H]8N[C@H](CC8)C7)=C6CC3)=CC(O)=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ras
Isoform
– K-Ras
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
