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Products Details
Product Description
– KRAS G12D inhibitor 12 is a potent inhibitor of KRAS G12D. The Ras family of proteins is an important intracellular signaling molecule that plays an important role in growth and development. KRAS G12D inhibitor 12 has the potential for the research of KRAS G12D-mediated cancer (extracted from patent WO2021108683A1, compound 134)[1].
Web ID
– HY-143606
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C23H21ClFN5O3
References
– [1]Jennifer PITZEN, et al. Covalent ras inhibitors and uses thereof. Patent WO2021108683A1.
CAS Number
– 2648552-54-7
Molecular Weight
– 469.90
SMILES
– O=C([C@@H]1CN1)N2CCN3C4=NC=NC5=C4C(OCC[C@@H]3C2)=C(C(C6=C(C=CC=C6O)F)=C5)Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ras
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
