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KRAS G12C inhibitor 56
Products Details
Product Description
– KRAS G12C inhibitor 56 (compound IC-6) is a potent SOS1 inhibitor with an IC50 of 1.6 nM. KRAS G12C inhibitor 56 can be used in cancer research[1].
Web ID
– HY-148261
Shipping
– Room temperature
Molecular Formula
– C32H39N7O4S
References
– [1]Jason ABBOTT, et al. Annulated 2-amino-3-cyano thiophenes and derivatives for the treatment of cancer. Patent WO2021245051A1.
CAS Number
– 2749963-77-5
Molecular Weight
– 617.76
SMILES
– C=CC(N1CCC(CC1)OC2=NC(C3=CC([C@@]4(C)CCCC5=C4C(C#N)=C(S5)N)=NO3)=NC(O[C@H]([C@@H]6CCCN6C)C)=C2)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ras
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.