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Products Details
Product Description
– KRAS G12C inhibitor 50 (Example 4) is a KRAS G12C inhibitor with an IC50 of 46.7 nM[1].
Web ID
– HY-147631
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C31H34N8O2
References
– [1]Guoliang Zhang, et al. Imidazotriazine and pyrrolopyrimidine derivatives as kras g12c inhibitors. WO2022028492A1.
CAS Number
– 2760354-12-7
Molecular Weight
– 550.65
SMILES
– C=CC(N1CCN(C[C@@H]1CC#N)C2=NC(OC[C@@H]3CCCN3C)=NN4C(CC5=C6C=CC=CC6=CC=C5)=CN=C24)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ras
Isoform
– K-Ras
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
