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Products Details
Product Description
– KRAS G12C inhibitor 41 is a potent inhibitor of KRAS G12C. The Ras family of proteins is an important intracellular signaling molecule that plays an important role in growth and development. KRAS G12C inhibitor 41 has the potential for the research of KRAS G12C-mediated cancer (extracted from patent WO2021129824A1, compound 121)[1].
Web ID
– HY-143596
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C36H37ClFN9O2
References
– [1]Yuli Xie, et al. Novel K-Ras G12C inhibitor. Patent WO2021129824A1.
CAS Number
– 2660014-65-1
Molecular Weight
– 682.19
SMILES
– CN1CCC[C@H]1COC2=NC(N3C[C@@H](N(CC3)C(C(C4=CN=CN=C4)=C)=O)CC#N)=C5C(CN(C6=CC=CC7=C6C(Cl)=C(F)C=C7)CC5)=N2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ras
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
