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KRAS G12C inhibitor 28
$850 – $3,000
Products Details
Product Description
– KRAS G12C inhibitor 28 is a KRAS G12C inhibitor with an IC50 of 57 nM. KRAS G12C inhibitor 28 has antitumor effects (WO2021113595A1; Example 1)[1].
Web ID
– HY-142460
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C33H36F2N5O4P
References
– [1]Don Zhang, et al. Phosphorus derivatives as kras inhibitors. WO2021113595A1.
CAS Number
– 2649004-88-4
Molecular Weight
– 635.64
Compound Purity
– 99.94
SMILES
– O=C1N(C2=C(C(C)C)C=C(P(C)(C)=O)C=C2C)C3=NC(C4=C(O)C=CC=C4F)=C(F)C=C3C(N5[C@@H](C)CN(C(C=C)=O)CC5)=N1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– Ras
Isoform
– K-Ras
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
