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Products Details
Product Description
– KRAS G12C inhibitor 25 is a KRAS G12C inhibitor. KRAS G12C inhibitor 25 inhibits SOSl-assisted GDP/GTP exchanging activity of KRAS-G12C mutant (IC50=0.48 nM). From WO2021216770A1 compound 3[1].
Web ID
– HY-145022
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C32H41N7O2
References
– [1]Yimin Qian, et al. Substituted tetrahydroquinazoline compounds as kras inhibitors. WO2021216770A1.
CAS Number
– 2734060-73-0
Molecular Weight
– 555.71
SMILES
– CN(CCC1)[C@@H]1COC2=NC(N3C[C@@H](N(CC3)C(C=C)=O)CC#N)=C4C(C[C@@](N5C6=CC=CC=C6CCC5)([H])CC4)=N2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ras
Isoform
– K-Ras
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
