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Products Details
Product Description
– KRAS G12C inhibitor 16 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 39, has an IC50 of 97 nM[1].
Web ID
– HY-125874
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C24H21ClFN3O3
References
– [1]Jason Grant Kettle, et al. Tetracyclic compounds as inhibitors of g12c mutant ras protein, for use as anti-cancer agents. WO2019110751A1.
CAS Number
– 2349392-79-4
Molecular Weight
– 453.89
SMILES
– OC1=C(C2=C(C)C(N=CC3=C4N5[C@H](CN(C(C=C)=O)CC5)CO3)=C4C=C2Cl)C(F)=CC=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ras
Isoform
– K-Ras
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
