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KM-001
$760 – $6,200
Products Details
Product Description
– KM-001 is a potent and selective TRPV3 antagonist. KM-001 reduces Ca2+ flux in keratinocytes and decreases cell proliferation accompanied by normalization of keratinocyte differentiation markers[1].
Web ID
– HY-153275
Shipping
– Room temperature
Molecular Formula
– C26H25FN2O2
References
– [1]Kamari Pharma Ltd, et al. Study Designed to Evaluate the Safety and Efficacy of 1% Topical Formulation of KM-001 on Type 1 Punctate Palmoplantar Keratoderma or Pachyonychia Congenita Diseases.
CAS Number
– 2682864-35-1
Molecular Weight
– 416.49
SMILES
– OCC1=C([C@@H]2CN(CC2)C(C3=CC=C(C=N3)F)=O)C=CC(C4=C(C5CC5)C=CC=C4)=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– TRP Channel
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
