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Products Details
Product Description
– Keap1-Nrf2-IN-7 (compound 7v) is a potent Keap1-Nrf2 PPI (Keap1-Nrf2 protein−protein interaction) inhibitor with an IC50 of 0.45 µM[1].
Web ID
– HY-146577
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C31H29FN2O9S2
References
– [1]Lee S, et al. Structure-activity relationships of 1,4-bis(arylsulfonamido)-benzene or naphthalene-N,N’-diacetic acids with varying C2-substituents as inhibitors of Keap1-Nrf2 protein-protein interaction. Eur J Med Chem. 2022 Jul 5;237:114380.
CAS Number
– 2769963-42-8
Molecular Weight
– 656.70
SMILES
– CC1=CC=C(C=C1)S(=O)(N(C2=CC=C(C(OCC3=CC=C(C=C3)F)=C2)N(S(=O)(C4=CC=C(C=C4)C)=O)CC(O)=O)CC(O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Keap1-Nrf2
Pathway
– NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
