Products Details

Product Description

– KDM5B-IN-3 (Compound 5) is a histone lysine specific demethylase 5B (KDM5B/JARID1B) inhibitor with an IC50 of 9.32 μM. KDM5B-IN-3 can be used for the research of gastric cancer[1].

Web ID

– HY-146670

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C19H25ClN4O2

References

– [1]Bing Zhao, et al. Discovery of pyrazole derivatives as cellular active inhibitors of histone lysine specific demethylase 5B (KDM5B/JARID1B). Eur J Med Chem. 2020 Apr 15;192:112161.

CAS Number

– 1385101-10-9

Molecular Weight

– 376.88

SMILES

– CC(C1=NNC(C(NCC(N2CCOCC2)C3=C(C=CC=C3)Cl)=O)=C1)C

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Histone Demethylase

Isoform

– KDM5

Pathway

– Epigenetics

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

My Cart
Close Wishlist
Close Recently Viewed
Categories

Please fill out this form to request the file. We will send it to your Email address shortly. Thanks.

Please enable JavaScript in your browser to complete this form.

=

Please fill out this form to request the pricing.
We will send it to your email address shortly.
Thanks.

Please enable JavaScript in your browser to complete this form.

=