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Products Details
Product Description
– KDM5B-IN-3 (Compound 5) is a histone lysine specific demethylase 5B (KDM5B/JARID1B) inhibitor with an IC50 of 9.32 μM. KDM5B-IN-3 can be used for the research of gastric cancer[1].
Web ID
– HY-146670
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C19H25ClN4O2
References
– [1]Bing Zhao, et al. Discovery of pyrazole derivatives as cellular active inhibitors of histone lysine specific demethylase 5B (KDM5B/JARID1B). Eur J Med Chem. 2020 Apr 15;192:112161.
CAS Number
– 1385101-10-9
Molecular Weight
– 376.88
SMILES
– CC(C1=NNC(C(NCC(N2CCOCC2)C3=C(C=CC=C3)Cl)=O)=C1)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Histone Demethylase
Isoform
– KDM5
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
