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KDM4C-IN-1
$180 – $1,200
Products Details
Product Description
– KDM4C-IN-1 (Compound 4d) is a potent KDM4C inhibitor with an IC50 of 8 nM. KDM4C-IN-1 inhibits the growth of HepG2 and A549 cells with IC50s of 0.8 µM and 1.1 µM, respectively[1].
Web ID
– HY-146148
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C14H13N5O3
References
– [1]Vatroslav Letfus, et al. Rational design, synthesis and biological profiling of new KDM4C inhibitors. Bioorg Med Chem. 2020 Jan 1;28(1):115128.
CAS Number
– 52348-60-4
Molecular Weight
– 299.28
Compound Purity
– 98.99
SMILES
– O=C(C1=NC(C2=CC=C(OC)C=C2)=NN(C)C1=N3)N(C)C3=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 3 mg/mL
Target
– Histone Demethylase
Isoform
– KDM4
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
