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KDM4-IN-3
$125 – $1,050
Products Details
Product Description
– KDM4-IN-3 is a KDM4 inhibitor that exhibits improved potency in biochemical assays, is cell-permeable, and kills prostate cancer cells at low micromolar concentrations.
Web ID
– HY-132896
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C17H14N4O
References
– [1]Carter DM, et al. Enhanced Properties of a Benzimidazole Benzylpyrazole Lysine Demethylase Inhibitor: Mechanism-of-Action, Binding Site Analysis, and Activity in Cellular Models of Prostate Cancer. J Med Chem. 2021 Oct 14;64(19):14266-14282.
CAS Number
– 1068515-53-6
Molecular Weight
– 290.32
Compound Purity
– 99.34
SMILES
– OC1=C(C2=CC=CC=C2)C(C)=NN1C3=NC4=CC=CC=C4N3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 125 mg/mL (ultrasonic)
Target
– Histone Demethylase
Isoform
– KDM4
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
