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Products Details
Product Description
– K027 is a potent reactivator of Organophosphates (OP)-inhibited acetylcholinesterase (AChE). K027 can be used for the research of Alzheimer’s disease[1].
Web ID
– HY-144762
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C15H18Br2N4O2
References
– [1]Zuzana Kohoutova, et al. Charged pyridinium oximes with thiocarboxamide moiety are equally or less effective reactivators of organophosphate-inhibited cholinesterases compared to analogous carboxamides. J Enzyme Inhib Med Chem. 2022 Dec;37(1):760-767.
CAS Number
– 6586-37-4
Molecular Weight
– 446.14
SMILES
– O=C(C1=CC=[N+](CCC[N+]2=CC=C(C=C2)/C=N/O)C=C1)N.[Br-].[Br-]
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Cholinesterase (ChE)
Isoform
– AChE;BChE
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
