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Products Details
Product Description
– JX401 is a potent inhibitor of p38alpha, containing a 4-benzylpiperidine motif. p38alpha is hyperactive in inflammatory diseases, and various indications suggest that its inhibition would reverse inflammation. JX401 has the potential for the research of inflammation[1].
Web ID
– HY-108346
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C21H25NO2S
References
– [1]Friedmann Y, et al. JX401, A p38alpha inhibitor containing a 4-benzylpiperidine motif, identified via a novel screening system in yeast. Mol Pharmacol. 2006;70(4):1395-1405.
CAS Number
– 349087-34-9
Molecular Weight
– 355.49
SMILES
– O=C(C1=CC=C(SC)C=C1OC)N2CCC(CC3=CC=CC=C3)CC2
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– p38 MAPK
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
