Download Files:

JX401

SKU HY-108346-Get quote Category Tags , ,

Products Details

Product Description

– JX401 is a potent inhibitor of p38alpha, containing a 4-benzylpiperidine motif. p38alpha is hyperactive in inflammatory diseases, and various indications suggest that its inhibition would reverse inflammation. JX401 has the potential for the research of inflammation[1].

Web ID

– HY-108346

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C21H25NO2S

References

– [1]Friedmann Y, et al. JX401, A p38alpha inhibitor containing a 4-benzylpiperidine motif, identified via a novel screening system in yeast. Mol Pharmacol. 2006;70(4):1395-1405.

CAS Number

– 349087-34-9

Molecular Weight

– 355.49

SMILES

– O=C(C1=CC=C(SC)C=C1OC)N2CCC(CC3=CC=CC=C3)CC2

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– p38 MAPK

Pathway

– MAPK/ERK Pathway

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

My Cart
Close Wishlist
Close Recently Viewed
Categories

Please fill out this form to request the file. We will send it to your Email address shortly. Thanks.

Please enable JavaScript in your browser to complete this form.

Please fill out this form to request the pricing.
We will send it to your email address shortly.
Thanks.

Please enable JavaScript in your browser to complete this form.