Products Details

Product Description

– JTP-117968, a novel selective glucocorticoid receptor modulator (a non-steroidal SGRM, IC50 of 6.8 nM), exhibits improved transrepression/transactivation dissociation[1].

Web ID

– HY-125265

Shipping

– Room temperature

Applications

– Metabolism-sugar/lipid metabolism

Molecular Formula

– C31H31F3N2O2

References

– [1]Takafumi Kurimoto, et al. JTP-117968, a novel selective glucocorticoid receptor modulator, exhibits improved transrepression/transactivation dissociation. Eur J Pharmacol. 2017 May 15;803:179-186.

CAS Number

– 2250132-99-9

Molecular Weight

– 520.59

SMILES

– O=C(C(C=C1C2)=CC=C1[C@]3(CC4=CC=CC=C4)CC[C@@](C(F)(F)F)(O)C[C@@]3([H])C52CC5)NC6=CC=CN=C6C

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease

Solubility

– 10 mM in DMSO

Target

– Glucocorticoid Receptor

Pathway

– Immunology/Inflammation;Vitamin D Related/Nuclear Receptor

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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