Download Files:
JNJ-DGAT2-A
$200 – $1,650
Products Details
Product Description
– JNJ-DGAT2-A is a selective diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 value of 0.14 μM in human DGAT2-expressing Sf9 insect cell membranes. JNJ-DGAT2-A can be used for the research of triglyceride (TG) synthesis[1].
Web ID
– HY-110381
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C24H16BrFN4O2S
References
– [1]Qi J, et al. The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and -2. J Lipid Res. 2012 Jun;53(6):1106-16.
CAS Number
– 1962931-71-0
Molecular Weight
– 523.38
Compound Purity
– 98.11
SMILES
– BrC1=C(C=CC(C#N)=C1)OC2=C(C=C(C=C2)/C=C3SC(NCCC4=CC=CC=N4)=NC3=O)F
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– DMSO : 3.33 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Acyltransferase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
