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Products Details
Product Description
– JNJ-42314415 is a centrally active phosphodiesterase 10A (PDE10A) inhibitor, with Ki values of 35 nM and 64 nM for human recombinant PDE10A and rPDE10A, respectively[1].
Web ID
– HY-123743
Shipping
– Room temperature
Molecular Formula
– C19H23N5O2
References
– [1]Anton A H P Megens, et al. Pharmacology of JNJ-42314415, a centrally active phosphodiesterase 10A (PDE10A) inhibitor: a comparison of PDE10A inhibitors with D2 receptor blockers as potential antipsychotic drugs. J Pharmacol Exp Ther. 2014 Apr;349(1):138-54.
CAS Number
– 1334165-90-0
Molecular Weight
– 353.42
SMILES
– CC1=C(N2C(C(N3CCOCC3)=NC=C2)=N1)C4=CC=C(N=C4)CCOC
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Phosphodiesterase (PDE)
Isoform
– PDE10
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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