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Products Details
Product Description
– JNJ-26076713 is a potent and orally active alpha V integrin antagonist with IC50 values of 2.3 nM and 6.3 nM for alpha(V)beta(3) and alpha(V)beta(5), respectively. JNJ-26076713 inhibits retinal neovascularization[1].
Web ID
– HY-116030
Shipping
– Room temperature
Molecular Formula
– C29H38N4O3
References
– [1]Santulli RJ, et, al. Studies with an orally bioavailable alpha V integrin antagonist in animal models of ocular vasculopathy: retinal neovascularization in mice and retinal vascular permeability in diabetic rats. J Pharmacol Exp Ther. 2008 Mar;324(3):894-901.
CAS Number
– 669076-03-3
Molecular Weight
– 490.64
SMILES
– O=C(C[C@@H]([C@H]1CNC2=C(C1)C=CC=C2)CC3CCN(CC3)C(CCC4=CC=C5CCCN=C5N4)=O)O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Integrin
Isoform
– αvβ3;αvβ5
Pathway
– Cytoskeleton
Product type
– Reference compound
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