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JI-101
$90 – $950
Products Details
Product Description
– JI-101 is an orally available multi-kinase inhibitor of VEGFR2, PDGFRβ and EphB4 with potent anti-cancer activity.
Web ID
– HY-16265
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C22H20BrN5O2
References
– [1]Gurav SD, et al. Pharmacokinetics, tissue distribution and identification of putative metabolites of JI-101 – a novel triple kinase inhibitor in rats. Arzneimittelforschung. 2012 Jan;62(1):27-34.
CAS Number
– 900573-88-8
Molecular Weight
– 466.33
Compound Purity
– 99.43
SMILES
– O=C(NC1=CC(Br)=CC=C1OC)NC2=CC=CC3=C2C=CN3CC4=CC(N)=NC=C4
Clinical Information
– Phase 2
Research Area
– Cardiovascular Disease; Cancer
Solubility
– DMSO : ≥ 100 mg/mL
Target
– Ephrin Receptor;PDGFR;VEGFR
Isoform
– PDGFRβ;VEGFR2/KDR/Flk-1
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
