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JG-231
$380 – $3,200
Products Details
Product Description
– JG-231 is an analogue of JG-98 with anticancer effects. JG-231 inhibits the interaction of Hsp70-BAG3. JG-231 inhibits MDA-MB-231 heterograft tumor models of triple negative breast cancer (TNBC)[1].
Web ID
– HY-124611
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Molecular Formula
– C22H18BrCl2N3OS4
References
– [1]Shao H, et al. Exploration of Benzothiazole Rhodacyanines as Allosteric Inhibitors of Protein-Protein Interactions with Heat Shock Protein 70 (Hsp70). J Med Chem. 2018 Jul 26;61(14):6163-6177.
CAS Number
– 1627126-59-3
Molecular Weight
– 619.47
Compound Purity
– 98.81
SMILES
– O=C1N(CC)/C(S/C1=C2SC3=CC(Cl)=CC=C3N/2C)=C/C4=[N+](CC5=CC=C(Br)S5)C=CS4.[Cl-]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 2 mg/mL (ultrasonic)
Target
– HSP
Isoform
– HSP70
Pathway
– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
