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JFD00244
$50 – $137
Products Details
Product Description
– JFD00244 is a sirtuin 2 (SIRT2) inhibitor, with anti-tumor effect. JFD00244 is also a Nsp-16 inhibitor against SARS-CoV-2[1][2].
Web ID
– HY-108986
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C30H26N2O4
References
– [1]Ciarlo C, A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development. Elife. 2017 Aug 23;6. pii: e29145.|[2]Shankar U, et al. Potential Drugs Targeting Nsp16 Protein May Corroborates a Promising Approach to Combat SARSCoV-2 Virus. ChemRxiv. Cambridge: Cambridge Open Engage; 2020; This content is a preprint and has not been peer-reviewed. |[3]Kim Dae Jung, et al. Pharmaceutical composition for preventing and treating prostate cancer: World Intellectual Property Organization, WO2014065537[P]. 2014-05-01.
CAS Number
– 96969-83-4
Molecular Weight
– 478.54
Compound Purity
– 98.03
SMILES
– O=C1C2=C(C=CC=C2)C(C3=C(NCCC4=CC=C(O)C=C4)C=CC(NCCC5=CC=C(O)C=C5)=C13)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 50 mg/mL (ultrasonic)|H2O : 1 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– SARS-CoV;Sirtuin
Pathway
– Anti-infection;Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
