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JD-5037
$108 – $828
Products Details
Product Description
– JD-5037 is a potent CB1R antagonist with an IC50 of 1.5 nM.
Web ID
– HY-18697
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C27H27Cl2N5O3S
References
– [1]Chorvat RJ. Peripherally restricted CB1 receptor blockers. Bioorg Med Chem Lett. 2013 Sep 1;23(17):4751-60.|[2]Knani I, et al. Targeting the endocannabinoid/CB1 receptor system for treating obesity in Prader-Willi syndrome. Mol Metab. 2016 Oct 22;5(12):1187-1199.|[3]Mukhopadhyay B, et al. Cannabinoid receptor 1 promotes hepatocellular carcinoma initiation and progression through multiple mechanisms. Hepatology. 2015 May;61(5):1615-26.
CAS Number
– 1392116-14-1
Molecular Weight
– 572.51
Compound Purity
– 98.05
SMILES
– NC([C@H](C(C)C)/N=C(NS(=O)(C1=CC=C(Cl)C=C1)=O)N2N=C(C3=CC=C(Cl)C=C3)[C@@H](C4=CC=CC=C4)C2)=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease; Cancer
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– Cannabinoid Receptor
Isoform
– CB1
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
