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Products Details
Product Description
– JAK2/STAT3-IN-1 (compound (S)-10a) is a potent GP130 inhibitor with an IC50 of 3.04 µM. JAK2/STAT3-IN-1 shows anti-tumor activity[1].
Web ID
– HY-131194
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C34H35BrF3N5O2
References
– [1]Song D, et al. Discovery of bazedoxifene analogues targeting glycoprotein 130. Eur J Med Chem. 2020 Aug 1;199:112375.
CAS Number
– 2485758-50-5
Molecular Weight
– 682.57
SMILES
– O=C(N1N=C(C2=CC=C(C(F)(F)F)C=C2)C[C@H]1C3=CN(CC4=CC=C(OCCN5CCCCCC5)C=C4)C6=C3C=C(Br)C=C6)N
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Interleukin Related
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
