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JAK2 JH2 Tracer
$150 – $2,500
Products Details
Product Description
– JAK2 JH2 Tracer (Tracer 5) is a fluorescent probe for JAK2 JH2 domain, with a Kd of value 0.2 μM[1][2].
Web ID
– HY-102055
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Molecular Formula
– C38H27F2N7O6S
References
– [1]Newton AS, et al. JAK2 JH2 Fluorescence Polarization Assay and Crystal Structures for Complexes with Three Small Molecules. ACS Med Chem Lett. 2017 May 17;8(6):614-617.|[2]Ihle JN, Gilliland DG. Jak2: normal function and role in hematopoietic disorders. Curr Opin Genet Dev. 2007 Feb;17(1):8-14.
CAS Number
– 2101955-00-2
Molecular Weight
– 747.73
Compound Purity
– 98.03
SMILES
– S=C(NC1=CC2=C(C3(C4=C(OC5=C3C=CC(O)=C5)C=C(O)C=C4)OC2=O)C=C1)N(CC6=CC=C(NC7=NN(C(C8=C(F)C=CC=C8F)=O)C(N)=N7)C=C6)C
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– DMSO : ≥ 83.3 mg/mL
Target
– JAK
Pathway
– Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Product type
– Dye Reagents
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
