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JAK1-IN-8
$50 – $540
Products Details
Product Description
– JAK1-IN-8, a potent JAK1 inhibitor (IC50<500 nM), compound 28, extracted from patent WO2016119700A1[1].
Web ID
– HY-139423
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C22H23FN4O3S
References
– [1]Jin Li, et al. Composés d’imidazo[1,2-a]pyridin-2-ylamine substitués, compositions pharmaceutiques et leurs méthodes d’utilisation. Patent WO2016119700A1.
CAS Number
– 1973485-18-5
Molecular Weight
– 442.51
Compound Purity
– 95.0
SMILES
– O=C(C1CC1)NC2=CN3C(C4=CC(F)=C(CN5CCS(=O)(CC5)=O)C=C4)=CC=CC3=N2
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– DMSO : 125 mg/mL (ultrasonic)
Target
– JAK
Isoform
– JAK1;JAK2;JAK3
Pathway
– Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
