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JAK-IN-5 (hydrochloride)
SKU
HY-111471A-10 mg
Category Reference compound
Tags Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt, Inflammation/Immunology, JAK
$450 – $3,800
Products Details
Product Description
– JAK-IN-5 hydrochloride is an inhibitor of JAK extracted from patent US20170121327A1, compound example 283[1].
Web ID
– HY-111471A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C27H32ClFN6O
References
– [1]Paul R. Fatheree, et al. JAK Kinase Inhibitor Compounds for Treatment of Respiratory Disease. US20170121327A1.|[2]Venkat R, et al. Methods of treatment using a jak inhibitor compound. US20180311226.
CAS Number
– 2751323-21-2
Molecular Weight
– 511.03
Compound Purity
– 99.86
SMILES
– CN1CCC(N2CC(N=C(C3=NNC4=C3C=CC(C5=C(CC)C=C(O)C(F)=C5)=C4)N6)=C6CC2)CC1.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 5 mg/mL (ultrasonic)|H2O : 0.5 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– JAK
Pathway
– Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.