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Products Details
Product Description
– JAK-IN-4 is a proagent of a JAK inhibitor, effective in murine collagen induced arthritis model[1].
Web ID
– HY-111749
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C18H19N4Na2O6P
References
– [1]Spergel SH, et al. Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis. ACS Med Chem Lett. 2019 Feb 13;10(3):306-311.
CAS Number
– 1400877-37-3
Molecular Weight
– 464.32
SMILES
– O=P(OC[C@@H](NC1=C(C(N)=O)C=NN2C1=CC(C3=CC=CC=C3)=C2)[C@H](O)C)(O[Na])O[Na]
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– JAK
Isoform
– JAK
Pathway
– Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
