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Products Details
Product Description
– JAK-IN-31 (Example 75) is a JAK inhibitor with IC50 ranges of ≤0.01µM, ≤0.01µM, 0.01-0.1 µM and ≤0.01µM for JAK1, JAK2, JAK3 and Tyk2 respectively. JAK-IN-31 can be used in cancer research[1].
Web ID
– HY-156706
Shipping
– Room temperature
Molecular Formula
– C21H19N7O2S2
References
– [1]David Randolph ANDERSON, et al. Substituted sulfonamide pyrrolopyridines as jak inhibitors. Patent WO2021022178A1.
CAS Number
– 2597016-88-9
Molecular Weight
– 465.55
SMILES
– CC1=NN=C(S1)C2=CN=C3C(C=CN3)=C2N[C@@H]4C[C@@H](C4)NS(=O)(C5=CC(C#N)=CC=C5)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– JAK
Pathway
– Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
