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JAK-IN-26
$109 – $1,980
Products Details
Product Description
– JAK-IN-26 (Compound 2) is a JAK inhibitor. JAK-IN-26 inhibits IFN-α2b induced p-STAT3 in Jurkat cells (IC50: 17.2 nM). JAK-IN-26 has superior pharmacokinetic properties[1].
Web ID
– HY-153701
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C22H24N6O3
References
– [1]Zhou M, et al. Pyridine derivatives as TYK2 kinase inhibitors and preparation thereof. China, CN113563309 A 2021-10-29.|[2]Zhou Mengguang. Pyridine derivative and preparation method and application thereof. Patent. CN113563309.
CAS Number
– 2417134-93-9
Molecular Weight
– 420.46
Compound Purity
– 98.00
SMILES
– O=C(C1CC1)NC2=NC=C(C(NC3=CC=CC(C4=NN(C)C=N4)=C3OC)=C2)C(CC)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– JAK
Pathway
– Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
