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Products Details
Product Description
– JAK-IN-18 is a potent inhibitor of JAK. JAK-IN-18 is useful for the research of multiple diseases, particularly ocular, skin, and respiratory diseases (extracted from patent WO2018204238A1, compound 1)[1].
Web ID
– HY-144058
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C27H28F2N6O3
References
– [1]Paul R. Fatheree, et al. Fused imidazo-piperidine jak inhibitor compound. Patent WO2018204238A1.
CAS Number
– 2247925-32-0
Molecular Weight
– 522.55
SMILES
– FC1=CC(C2=CC(F)=C(O)C=C2CC)=CC3=C1C(C(N4)=NC5=C4CN(C(CN6CCOCC6)=O)CC5)=NN3
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– JAK
Pathway
– Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
