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Products Details
Product Description
– JAK-2/3-IN-2 (Compound 3h) is a JAK2 and JAK3 inhibitor with IC50s of 23.85 nM and 18.9 nM, respectively[1].
Web ID
– HY-151256
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C19H19ClN2OS
References
– [1]Sanachai K, et al. Pharmacophore-Based Virtual Screening and Experimental Validation of Pyrazolone-Derived Inhibitors toward Janus Kinases. ACS Omega, 2022.
CAS Number
– 2170398-48-6
Molecular Weight
– 358.88
SMILES
– O=C1N(C2=CC=CC=C2Cl)N(CC)C(C)=C1SC3=CC=C(C)C=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– JAK
Isoform
– JAK2;JAK3
Pathway
– Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
