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Products Details
Product Description
– JAK-2/3-IN-1 is a potent JAK-2 and JAK-3 inhibitor extracted from patent US8163732B2, compound 46, has Kis of <250 nM for both isoforms[1].
Web ID
– HY-10652
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C20H12ClN3O
References
– [1]Youssef Bennani, et al. Tricyclic heteroaryl compounds useful as inhibitors of Janus kinase. US8163732B2.
CAS Number
– 1036241-36-7
Molecular Weight
– 345.78
SMILES
– OC1=CC=C(C2=NC3=CC=CC=C3C4=C5C(NC=C25)=NC=C4)C(Cl)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– JAK
Isoform
– JAK2;JAK3
Pathway
– Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
