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Products Details
Product Description
– J27644 is a potent HDAC inhibitor. J27644 mitigates TGF-β-induced pulmonary fibrosis[1].
Web ID
– HY-155699
Shipping
– Room temperature
Molecular Formula
– C16H12ClN3O4
References
– [1]Yu WC, et, al. Discovery of HDAC6, HDAC8, and 6/8 Inhibitors and Development of Cell-Based Drug Screening Models for the Treatment of TGF-β-Induced Idiopathic Pulmonary Fibrosis. J Med Chem. 2023 Aug 10;66(15):10528-10557.|[2]Yu WC, et, al. Discovery of HDAC6, HDAC8, and 6/8 Inhibitors and Development of Cell-Based Drug Screening Models for the Treatment of TGF-β-Induced Idiopathic Pulmonary Fibrosis. J Med Chem. 2023 Aug 10;66(15):10528-10557.
Molecular Weight
– 345.74
SMILES
– O=C(NC1=O)C2=CC=CC(Cl)=C2N1CC3=CC=C(C=C3)C(NO)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– HDAC
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
