Download Files:
Products Details
Product Description
– J1038 (T 5979345) is a selective HDAC8 inhibitor. J1038 binds the catalytic zinc ion of Schistosoma mansoni HDAC8 (smHDAC8)[1].
Web ID
– HY-111028
Shipping
– Room temperature
Molecular Formula
– C10H10N2O3S
References
– [1]Marek M, et al. Structural basis for the inhibition of histone deacetylase 8 (HDAC8), a key epigenetic player in the blood fluke Schistosoma mansoni. PLoS Pathog. 2013;9(9):e1003645.
CAS Number
– 949727-86-0
Molecular Weight
– 238.26
SMILES
– O=C(C1=CC=C(SC(C)C(N2)=O)C2=C1)NO
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– HDAC
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
