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Ixabepilone
$119 – $440
Products Details
Product Description
– Ixabepilone (BMS-247550) is an orally bioavailable microtubule inhibitor, which binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arrests cells in the G2-M phase of the cell cycle and induces tumor cell apoptosis.
Web ID
– HY-10222
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C27H42N2O5S
References
– [1]John T. Hunt Discovery of Ixabepilone. Mol Cancer Ther February 2009 8; 275
CAS Number
– 219989-84-1
Molecular Weight
– 506.70
Compound Purity
– 99.93
SMILES
– O=C([C@@H]([C@H]([C@H](CCC[C@]1(O[C@]1(C[C@H](N2)/C(C)=C/C3=CSC(C)=N3)[H])C)C)O)C)C(C)([C@H](CC2=O)O)C
Clinical Information
– Launched
Research Area
– Cancer
Solubility
– DMSO : 83.33 mg/mL (ultrasonic)
Target
– Apoptosis;Bacterial;Microtubule/Tubulin
Pathway
– Anti-infection;Apoptosis;Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
