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Products Details
Product Description
– ITK/TRKA-IN-1 is a dual inhibitor of IL-2-inducible T-cell kinase (ITK) and tropomyosin receptor kinase A (TRKA) with an IC50 value of 1.0 nM and 96 % inhibition, respectively.
Web ID
– HY-141864
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C25H30F2N6O2
References
– [1]Bagley SW, et al. Benzimidazole Derivatives. WO2021124155A1.
CAS Number
– 2655557-54-1
Molecular Weight
– 484.54
SMILES
– C[C@@]12CC3=C(C(C4=NC5=C(N4)C=C(C(N(C([C@@H](N6CCOCC6)C)=O)C)=C5)C)=NN3)C[C@@H]1C2(F)F
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Itk
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
