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Isotretinoin
$60 – $126
Products Details
Product Description
– Isotretinoin (13-cis-Retinoic acid) is an orally active vitamin A derivative and is often be used for the research of severe acne. Isotretinoin also shows anticancer activity[1][2].
Web ID
– HY-15127
Storage Temperature
– -20°C (Powder, protect from light, stored under nitrogen)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H28O2
References
– [1]Layton A. The use of isotretinoin in acne. Dermatoendocrinol. 2009 May;1(3):162-9.|[2]Dahl AR, et al. Inhaled isotretinoin (13-cis retinoic acid) is an effective lung cancer chemopreventive agent in A/J mice at low doses: a pilot study. Clin Cancer Res. 2000 Aug;6(8):3015-24|[3]Bergoli RD, et al. Isotretinoin effect on alveolar repair after exodontia–a study in rats. Oral Maxillofac Surg. 2011 Jun;15(2):85-92.|[4]RamÃrez-Flores PN, et al. Isotretinoin and Thalidomide Down-Regulate c-MYC Gene Expression and Modify Proteins Associated with Cancer in Hepatic Cells. Molecules. 2021 Sep 22;26(19):5742.
CAS Number
– 4759-48-2
Molecular Weight
– 300.44
Compound Purity
– 99.53
SMILES
– CC1(C)C(/C=C/C(C)=C/C=C/C(C)=CC(O)=O)=C(C)CCC1
Clinical Information
– Launched
Research Area
– Cancer
Target
– Autophagy;Endogenous Metabolite;RAR/RXR
Isoform
– Human Endogenous Metabolite
Pathway
– Autophagy;Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
