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Isosinensetin
SKU
HY-N1941-10 mg
Category Natural Products
Tags Anti-infection;Membrane Transporter/Ion Channel, Bacterial;P-glycoprotein, Infection; Inflammation/Immunology
$178 – $514
Products Details
Product Description
– Isosinensetin, a polymethoxylated flavone extracted from pericarpium citri reticulatae viride, exhibits inhibition on P-glycoprotein (P-gp) in MDR1-MDCKII cells[1][2].
Web ID
– HY-N1941
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C20H20O7
References
– [1]Wang D, et al. Identification of polymethoxylated flavones from green tangerine peel (Pericarpium Citri Reticulatae Viride) by chromatographic and spectroscopic techniques. J Pharm Biomed Anal. 2007 May 9;44(1):63-9.|[2]Bai J, et al. Inhibitory effects of flavonoids on P-glycoprotein in vitro and in vivo: Food/herb-drug interactions and structure-activity relationships. Toxicol Appl Pharmacol. 2019 Apr 15;369:49-59.|[3]Kanda Panthong, et al. Prenylated flavone from roots of a hybrid between Artocarpus heterophyllus and Artocarpus integer and its biological activities. Journal of the Brazilian Chemical Society. Print version ISSN 0103-5053
CAS Number
– 17290-70-9
Molecular Weight
– 372.37
Compound Purity
– 99.65
SMILES
– O=C1C=C(C2=CC=C(OC)C(OC)=C2)OC3=C(OC)C(OC)=CC(OC)=C13
Clinical Information
– No Development Reported
Research Area
– Infection; Inflammation/Immunology
Solubility
– DMSO : 12.5 mg/mL (ultrasonic)
Target
– Bacterial;P-glycoprotein
Pathway
– Anti-infection;Membrane Transporter/Ion Channel
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.