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Isogarcinol
$360 – $900
Products Details
Product Description
– Isogarcinol (Cambogin) is a potent AChE and BChE inhibitor, with IC50 values of 1.13 and 8.30 μM, respectively. Isogarcinol also shows leishmanicidal activity, with an IC50 of 0.33 μM against L. donovani[1].
Web ID
– HY-127087
Shipping
– Room temperature
Molecular Formula
– C38H50O6
References
– [1]Lenta BN, et al. Leishmanicidal and cholinesterase inhibiting activities of phenolic compounds from Allanblackia monticola and Symphonia globulifera. Molecules. 2007 Jul 20;12(8):1548-57.
CAS Number
– 71117-97-0
Molecular Weight
– 602.80
SMILES
– O=C1[C@@]23C(OC(C)([C@H](C3)C/C=C(C)C)C)=C(C([C@@]1(C(C)([C@@H](C2)C/C=C(C)C)C)C/C=C(C)C)=O)C(C4=CC(O)=C(C=C4)O)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Cholinesterase (ChE);Parasite
Isoform
– AChE;BChE;Leishmania
Pathway
– Anti-infection;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
