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Isoferulic acid
$50 – $55
Products Details
Product Description
– Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) is a cinnamic acid derivative that has antidiabetic activity. Isoferulic acid binds to and activates α1-adrenergic receptors (IC50=1.4 µM) to enhance secretion of β-endorphin (EC50=52.2 nM) and increase glucose use. Isoferulic acid also has anti-influenza virus activities.
Web ID
– HY-N0761
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C10H10O4
References
– [1]Liu IM, et al. Mediation of beta-endorphin by isoferulic acid to lower plasma glucose in streptozotocin-induced diabetic rats. J Pharmacol Exp Ther. 2003 Dec;307(3):1196-204.|[2]Sakai S, et al. Administration of isoferulic acid improved the survival rate of lethal influenza virus pneumonia in mice. Mediators Inflamm. 2001 Apr;10(2):93-6.
CAS Number
– 537-73-5
Molecular Weight
– 194.18
Compound Purity
– 99.98
SMILES
– O=C(O)/C=C/C1=CC=C(OC)C(O)=C1
Clinical Information
– No Development Reported
Research Area
– Infection; Endocrinology; Metabolic Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Adrenergic Receptor;Influenza Virus
Isoform
– α adrenergic receptor
Pathway
– Anti-infection;GPCR/G Protein;Neuronal Signaling
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
