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Products Details
Product Description
– (-)-Isodocarpin (Isodocarpin), a diterpenoid, is a potent melanogenesis inhibitor with an IC50 of 0.19 μM in B16 4A5 cells. (-)-Isodocarpin inhibits the expression of tyrosinase, tyrosine-related protein (TRP)-1, and TRP-2 mRNA[1].
Web ID
– HY-134046
Shipping
– Room temperature
Molecular Formula
– C20H26O5
References
– [1]Yoshiaki Manse, et al. Melanogenesis Inhibitory Activity of Diterpenoid and Triterpenoid Constituents from the Aerial Part of Isodon trichocarpus. Natural Product Communications. August 1, 2017.
CAS Number
– 10391-08-9
Molecular Weight
– 346.42
SMILES
– O[C@H]1[C@@]2([H])[C@]3(CO1)[C@@]4([H])[C@@]5(C(O[C@@]3([H])CCC2(C)C)=O)C[C@@](C(C5=O)=C)([H])CC4
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Melanocortin Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
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