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Products Details
Product Description
– isoCA-4, a Combretastatin A4 derivative, is a tubulin polymerization inhibitor. isoCA-4 has anti-proliferative activities[1].
Web ID
– HY-146506
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C18H20O5
References
– [1]Xiang-Yu Yan, et al. Design, synthesis, and biological evaluation of novel diphenylamine derivatives as tubulin polymerization inhibitors targeting the colchicine binding site. Eur J Med Chem. 2022 Apr 16;237:114372.
CAS Number
– 1067880-31-2
Molecular Weight
– 316.35
SMILES
– C=C(C1=CC(OC)=C(C(OC)=C1)OC)C2=CC(O)=C(C=C2)OC
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
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