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ISIS 104838
$500 – $1,800
Products Details
Product Description
– ISIS 104838 is an antisense oligonucleotide agent that reduces the production of tumor necrosis factor (TNF-alpha), a substance that contributes to joint pain and swelling in rheumatoid arthritis.
Web ID
– HY-145726
Storage Temperature
– -20°C (Powder, stored under nitrogen)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– N/A
References
– [1]Sewell KL, Geary RS, Baker BF, et al. Phase I trial of ISIS 104838, a 2′-methoxyethyl modified antisense oligonucleotide targeting tumor necrosis factor-alpha. J Pharmacol Exp Ther. 2002;303(3):1334-1343.
CAS Number
– 250755-32-9
Molecular Weight
– 7283.90
Compound Purity
– 93.70
SMILES
– [ISIS 104838]
Clinical Information
– Phase 2
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in H2O
Target
– TNF Receptor
Pathway
– Apoptosis
Product type
– Oligonucleotides
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
