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Irsogladine (maleate)
SKU
HY-B0327A-Get quote
Category Reference compound
Tags GPCR/G Protein;Metabolic Enzyme/Protease;Neuronal Signaling, Inflammation/Immunology, mAChR;Phosphodiesterase (PDE)
Web ID
– HY-B0327A
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C13H11Cl2N5O4
References
– [1]Ren, C.J., et al., Irsogladine maleate inhibits angiogenesis in wild-type and plasminogen activator-deficient mice. J Surg Res, 1998. 77(2): p. 126-31.|[2]Kawasaki, Y., et al., Irsogladine malate up-regulates gap junctional intercellular communication between pancreatic cancer cells via PKA pathway. Pancreas, 2002. 25(4): p. 373-7.|[3]Kyoi, T., et al., Phosphodiesterase inhibition by a gastroprotective agent irsogladine: preferential blockade of cAMP hydrolysis. Life Sci, 2004. 75(15): p. 1833-42.
CAS Number
– 84504-69-8
Molecular Weight
– 372.16
SMILES
– O=C(O)/C=CC(O)=O.NC1=NC(N)=NC(C2=CC(Cl)=CC=C2Cl)=N1
Clinical Information
– Launched
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– mAChR;Phosphodiesterase (PDE)
Isoform
– PDE4
Pathway
– GPCR/G Protein;Metabolic Enzyme/Protease;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.